Socio‐demographic and clinical factors influencing the adherence to treatment in Parkinson’s disease: the ADHESON study
Identifieur interne : 000152 ( Main/Exploration ); précédent : 000151; suivant : 000153Socio‐demographic and clinical factors influencing the adherence to treatment in Parkinson’s disease: the ADHESON study
Auteurs : F. Valldeoriola ; C. Coronell [Espagne] ; C. Pont ; M. T. Buongiorno ; A. Cámara ; C. Gaig ; Y. ComptaSource :
- European Journal of Neurology [ 1351-5101 ] ; 2011-07.
English descriptors
- KwdEn :
Abstract
Background: Symptoms of Parkinson’s disease (PD) are usually controlled by a continuous titration of medication and addition of multiple therapies over the course of the disease. Therapeutic complex schemes, polymedication, comorbidities and the number of medications required contribute to non‐adherence. Methods: This cross‐sectional survey was performed in 418 patients with PD on treatment with any antiparkinsonian medication. Patient adherence was assessed through physicians’ subjective perception and the Morisky–Green test (MGT). Several social, demographic and clinical features were correlated through bivariate and multivariate analyses. Results: According to the physician’s opinion 93.7%, and according to the MGT 60.4% of patients were adherent to parkinsonian therapy. The bivariate analysis showed greater adherence in patients with a high level of knowledge about the disease (62.8%), good clinical control (63.6%), a spouse or life partner (63%) and higher incomes (66%). Negative correlation with psychiatric symptoms was found. In relation to the MGT, the logistic regression model showed a negative correlation between cognitive deterioration and psychiatric pathology and adherence to therapy. Conclusions: The physician’s impression overestimated the compliance of patients when compared with an objective evaluation such as the MGT. Cognitive impairment and psychiatric symptoms are the clinical variables associated with a lower level of adherence.
Url:
DOI: 10.1111/j.1468-1331.2010.03320.x
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Socio‐demographic and clinical factors influencing the adherence to treatment in Parkinson’s disease: the ADHESON study</title>
<author><name sortKey="Valldeoriola, F" sort="Valldeoriola, F" uniqKey="Valldeoriola F" first="F." last="Valldeoriola">F. Valldeoriola</name>
</author>
<author><name sortKey="Coronell, C" sort="Coronell, C" uniqKey="Coronell C" first="C." last="Coronell">C. Coronell</name>
</author>
<author><name sortKey="Pont, C" sort="Pont, C" uniqKey="Pont C" first="C." last="Pont">C. Pont</name>
</author>
<author><name sortKey="Buongiorno, M T" sort="Buongiorno, M T" uniqKey="Buongiorno M" first="M. T." last="Buongiorno">M. T. Buongiorno</name>
</author>
<author><name sortKey="Camara, A" sort="Camara, A" uniqKey="Camara A" first="A." last="Cámara">A. Cámara</name>
</author>
<author><name sortKey="Gaig, C" sort="Gaig, C" uniqKey="Gaig C" first="C." last="Gaig">C. Gaig</name>
</author>
<author><name sortKey="Compta, Y" sort="Compta, Y" uniqKey="Compta Y" first="Y." last="Compta">Y. Compta</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:B21D6E1A582328949460123F386E257D55CB8F8E</idno>
<date when="2011" year="2011">2011</date>
<idno type="doi">10.1111/j.1468-1331.2010.03320.x</idno>
<idno type="url">https://api.istex.fr/document/B21D6E1A582328949460123F386E257D55CB8F8E/fulltext/pdf</idno>
<idno type="wicri:Area/Main/Corpus">001E36</idno>
<idno type="wicri:Area/Main/Curation">001B50</idno>
<idno type="wicri:Area/Main/Exploration">000152</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Socio‐demographic and clinical factors influencing the adherence to treatment in Parkinson’s disease: the ADHESON study</title>
<author><name sortKey="Valldeoriola, F" sort="Valldeoriola, F" uniqKey="Valldeoriola F" first="F." last="Valldeoriola">F. Valldeoriola</name>
<affiliation><wicri:noCountry code="subField">Catalonia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Coronell, C" sort="Coronell, C" uniqKey="Coronell C" first="C." last="Coronell">C. Coronell</name>
<affiliation wicri:level="3"><country xml:lang="fr">Espagne</country>
<wicri:regionArea>Medical Department, Boehringer Ingelheim Spain, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pont, C" sort="Pont, C" uniqKey="Pont C" first="C." last="Pont">C. Pont</name>
<affiliation><wicri:noCountry code="subField">Catalonia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Buongiorno, M T" sort="Buongiorno, M T" uniqKey="Buongiorno M" first="M. T." last="Buongiorno">M. T. Buongiorno</name>
<affiliation><wicri:noCountry code="subField">Catalonia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Camara, A" sort="Camara, A" uniqKey="Camara A" first="A." last="Cámara">A. Cámara</name>
<affiliation><wicri:noCountry code="subField">Catalonia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Gaig, C" sort="Gaig, C" uniqKey="Gaig C" first="C." last="Gaig">C. Gaig</name>
<affiliation><wicri:noCountry code="subField">Catalonia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Compta, Y" sort="Compta, Y" uniqKey="Compta Y" first="Y." last="Compta">Y. Compta</name>
<affiliation><wicri:noCountry code="subField">Catalonia</wicri:noCountry>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">European Journal of Neurology</title>
<idno type="ISSN">1351-5101</idno>
<idno type="eISSN">1468-1331</idno>
<imprint><publisher>Blackwell Publishing Ltd</publisher>
<pubPlace>Oxford, UK</pubPlace>
<date type="published" when="2011-07">2011-07</date>
<biblScope unit="volume">18</biblScope>
<biblScope unit="issue">7</biblScope>
<biblScope unit="page" from="980">980</biblScope>
<biblScope unit="page" to="987">987</biblScope>
</imprint>
<idno type="ISSN">1351-5101</idno>
</series>
<idno type="istex">B21D6E1A582328949460123F386E257D55CB8F8E</idno>
<idno type="DOI">10.1111/j.1468-1331.2010.03320.x</idno>
<idno type="ArticleID">ENE3320</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">1351-5101</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson’s disease</term>
<term>adverse effects</term>
<term>depression</term>
<term>management</term>
<term>medication</term>
<term>movement disorders</term>
<term>neurodegenerative disorders (other than dementia)</term>
<term>neurological disorders</term>
<term>psychiatric disorders</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Background: Symptoms of Parkinson’s disease (PD) are usually controlled by a continuous titration of medication and addition of multiple therapies over the course of the disease. Therapeutic complex schemes, polymedication, comorbidities and the number of medications required contribute to non‐adherence. Methods: This cross‐sectional survey was performed in 418 patients with PD on treatment with any antiparkinsonian medication. Patient adherence was assessed through physicians’ subjective perception and the Morisky–Green test (MGT). Several social, demographic and clinical features were correlated through bivariate and multivariate analyses. Results: According to the physician’s opinion 93.7%, and according to the MGT 60.4% of patients were adherent to parkinsonian therapy. The bivariate analysis showed greater adherence in patients with a high level of knowledge about the disease (62.8%), good clinical control (63.6%), a spouse or life partner (63%) and higher incomes (66%). Negative correlation with psychiatric symptoms was found. In relation to the MGT, the logistic regression model showed a negative correlation between cognitive deterioration and psychiatric pathology and adherence to therapy. Conclusions: The physician’s impression overestimated the compliance of patients when compared with an objective evaluation such as the MGT. Cognitive impairment and psychiatric symptoms are the clinical variables associated with a lower level of adherence.</div>
</front>
</TEI>
<affiliations><list><country><li>Espagne</li>
</country>
<region><li>Catalogne</li>
</region>
<settlement><li>Barcelone</li>
</settlement>
</list>
<tree><noCountry><name sortKey="Buongiorno, M T" sort="Buongiorno, M T" uniqKey="Buongiorno M" first="M. T." last="Buongiorno">M. T. Buongiorno</name>
<name sortKey="Camara, A" sort="Camara, A" uniqKey="Camara A" first="A." last="Cámara">A. Cámara</name>
<name sortKey="Compta, Y" sort="Compta, Y" uniqKey="Compta Y" first="Y." last="Compta">Y. Compta</name>
<name sortKey="Gaig, C" sort="Gaig, C" uniqKey="Gaig C" first="C." last="Gaig">C. Gaig</name>
<name sortKey="Pont, C" sort="Pont, C" uniqKey="Pont C" first="C." last="Pont">C. Pont</name>
<name sortKey="Valldeoriola, F" sort="Valldeoriola, F" uniqKey="Valldeoriola F" first="F." last="Valldeoriola">F. Valldeoriola</name>
</noCountry>
<country name="Espagne"><region name="Catalogne"><name sortKey="Coronell, C" sort="Coronell, C" uniqKey="Coronell C" first="C." last="Coronell">C. Coronell</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000152 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000152 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= ParkinsonV1 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:B21D6E1A582328949460123F386E257D55CB8F8E |texte= Socio‐demographic and clinical factors influencing the adherence to treatment in Parkinson’s disease: the ADHESON study }}
This area was generated with Dilib version V0.6.23. |